ҚОРАМОЛЛАР ТЕЙЛЕРИОЗИНИ ДАВОЛАШДА ПИРОГАРД 2,4 ПРЕПАРАТИНИНГ САМАРАДОРЛИГИ

Abstract

This article presents a study on the therapeutic efficacy of the drug Pyrоgard 2.4 in 8 head of cattle spontaneously infected with theileriosis at the “Gʻarezsizlik” farm in the Chimbay district. In animals with mild to moderate clinical forms of the disease, body temperature ranged from 40.5 to 40.9 °C, and parasitemia levels were 0.08–0.01%; in severe cases, temperature ranged from 40.9 to 41.6 °C, with parasitemia reaching 17–22%. Peripheral blood smears were prepared, stained using the Romanowsky–Giemsa method, and microscopic analysis confirmed the presence of the theileriosis pathogen Th. annulata. The experiments were conducted in two groups (n = 4). In the first experimental group, cattle received Pyrоgard 2.4 intramuscularly once at a dosage of 1 ml per 20 kg of body weight in the form of a 7% solution. In the second group, the drug was administered at the same dosage and concentration but with a 24-hour interval. Along with the specific drug, symptomatic treatments were also applied. Based on the results of the study, it was determined that under field conditions, a single administration of Pyrоgard 2.4 at a dosage of 1.0 ml per 20 kg of body weight provides high therapeutic effectiveness in cattle spontaneously infected with theileriosis in mild clinical form. In severe cases, administering the drug at the same dose but with a 24-hour interval resulted in maximum (100%) effectiveness.